Description
Product Characteristics:
In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved cytoplasmic region called the death domain?. DAPL1 (Death-associated protein-like 1), also known as EEDA (Early epithelial differentiation-associated protein), is a 107 amino acid protein that is expressed in hair follicles and is thought to function in a similar manner to DAP-1, possibly participating in the early stages of epithelial differentiation and/or apoptosis.
Subcellular location: Cytoplasm, Nucleus, Cell membrane
Synonyms: dapL1, DAPL1_HUMAN, death associated protein-like 1, Death-associated protein-like 1, Early epithelial dferentiation-associated protein, EEDA, RP23-151F21.4.
Target Information: May play a role in the early stages of epithelial differentiation or in apoptosis (By similarity)